Authors are encouraged to submit digital art. The following resources offer help on preparing digital art. Specific instructions on acceptable software is available at the web sites.

CJS Web Site	http://cjs.cadmus.com/da
E-mail	digitalart{at}cadmus.com
Digital Art Help Line	1-800-257-5529, ext. 6985 (inside the U.S.), 410-691-6985 (outside the U.S.)

Submission Requirements

Hard copies: Authors must provide two (2) original hard copies of each figure for the printer. Label the back of each, respectively, "Printer's Copy 1" and "Printer's Copy 2." This hard copy will be scanned if the disk cannot be used.

Acceptable formats: 1) TIFF: a) Adobe Photoshop (line art and halftones only); b) CorelDRAW (halftones only); c) Generated by scanner (success rates in production will vary). 2) EPS: a) Adobe Photoshop; b) Adobe Illustrator; c) Macromedia FreeHand; d) QuarkXPress.

Acceptable systems: Macintosh, MD-DOS, or Windows.

Acceptable compression: PKZIP or WINZIP for DOS or Windows; StuffIt for Macintosh; self-extracting compression software.

Resolution: at least 300 dpi for halftones; 600 dpi for lettering; 1000 dpi for line art (1200 dpi preferred).

Acceptable media: 3.5" diskettes; 44-MB, 88-MB, or 200-MB SyQuest cartridge; 5-1/4" 281-MB/512-K sectors magneto-optical disk; CD-ROM.

Identification information: Provide a label showing the name of the software and the versions used to create the images and compress the file(s), the file name(s), the manuscript number, and the corresponding author's last name. The figures must not be submitted on the same disk as the manuscript. Place only one figure into each file.

Sizing the figure: The author is responsible for providing digital art that has been properly sized, cropped, and has adequate space between images. Plan the size of the figure to fill 1, 1 1/2, or 2 columns in the printed journal.

Columns	Picas	Centimeters	Inches
1	21	8.9	3.5
1 1/2	30	12.7	5.0
2	43.6	18.4	7.25

Special requirements for 4-color art: Submit digital files in EPS format generated from Adobe Photoshop, Adobe Illustrator, and QuarkXPress. Save files in CMYK mode (cyan-magenta-yellow-black). Color saturation of the shadow portion cannot exceed 280% (% cyan + % magenta + % yellow + % black cannot exceed 280%).

General: Add type to a scanned image by importing the TIFF scan into a page layout program (such as Macromedia FreeHand) and create PostScript type there. Scan line art at 1200 dpi and save in bitmap mode. Scan halftones at 300 dpi and save as grayscale images. With the exception of QuarkXPress and Adobe Photoshop, place and lock the images in the upper left-hand corner. Note that the screen fuline for all art is 150 lines per inch. Follow all figure guidelines specified in the Figure section below. Do not number figures; figure order may change during copy editing. Never send your only copy of a file. Label and lock your disk.

Figures

Produce original art at the size it should appear in the printed journal. Artwork must not be larger than journal page size. In most cases, figures should be prepared for 1-column width. Figures that should appear as 1 column should be 3 1/2" wide (8.9 cm); 1 1/2-column figures should be 5" wide (12.7 cm); 2-column figures should be 7 1/4" wide (18.4 cm). Figures should not exceed the standard 8 1/2" by 11" page size. Do not mount figures on cardboard or thick paper.

Use the highest resolution on the printer or graphics plotter (600 dpi or greater is preferred). Maximize the black and white contrast (toner level should be high). Use high quality laser printer paper.

At 100% size, no lettering should be smaller than 8 point (0.3 cm high) or larger than 12 point (0.4 cm high). Use bold and solid lettering. Lines should be thick, solid, and no less than 1 point rule. Avoid the use of reverse type (white lettering on a darker background). Avoid lettering on top of shaded or textured areas.

Avoid the use of shading, but if unavoidable, use a coarse rather than a fine screen setting (80-100 line screen is preferred). Avoid 1-20% and 70-99% shading; make differing shades vary by at least 20%, i.e. 25%, 45%, 65%. Instead of shading, denote variation in graphs or drawings by cross-hatching; solid black; or verticle, horizontal, or diagonal striping. Avoid the use of dots.

Laser printed or clearly photocopied figures are acceptable for three sets of figures, provided that these copies suffer no significant quality loss and may be easily interpreted by reviewers in evaluation of the manuscript. In general, quality loss in photocopies is more acceptable for line drawings and graphs than for gels or photographs. It is advisable to use a color copier for photocopies of color figures.

Original half-tones of gels must be submitted in place of computer-generated gels.

For grouped figures, indicate the layout in a diagram. Indicate magnification in the legends and by internal reference markers in the photographs. Their length should represent the fraction or multiple of a micrometer, appropriate to the magnification. Keep wording on figures to a minimum, and confine any explanation of figures to their separate-page legends. Label only one vertical and one horizontal side of a figure. If figures are grouped, place them so that they can be printed in 1-column width with uniform margins. Freehand lettering or drawing is unacceptable.

Graphs whose axis measures contain very large or small numbers should convert to easily readable notations. Example: For an ordinate range of "counts per minute" values from 1,000 to 20,000, the true value may be multiplied by 10^-3 (scale would read from 1 to 20) and the ordinate axis display "cpm (x10^-3)." Similarly, for a Scatchard plot with values ranging from 0.1 to 2 femtomolar (10^-15m), the scale may run from 0.1 to 2 with the abscissa labeled "M(x10¹⁵)." Three-dimensional bar graphs will not be published if the information they refer to is only two-dimensional.