Nuclear Receptor Coregulators: Cellular and Molecular Biology1
Neil J. McKenna,
Rainer B. Lanz and
Bert W. O’Malley
Department of Cell Biology, Baylor College of Medicine, Houston,
Texas 77030
I. Introduction
A. The nuclear receptor superfamily
B. Generaltranscription factors (GTFs)
II. Nuclear Receptor Coactivators
A. Background
B. Receptor-associated proteins and coactivators
III. Nuclear Receptor Corepressors
A. Background
B. Corepressors
IV. Nuclear Receptors and Chromatin
A. Background
B. TheMMTV and TRßA promoters
C. Coactivators and acetylation
D. Chromatin-remodeling proteins
E. Corepressors and deacetylation
V. Concluding Remarks
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E. Charmandari, T. Kino, T. Ichijo, K. Zachman, A. Alatsatianos, and G. P. Chrousos Functional Characterization of the Natural Human Glucocorticoid Receptor (hGR) Mutants hGR{alpha}R477H and hGR{alpha}G679S Associated with Generalized Glucocorticoid Resistance
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M. C. Velarde, M. Iruthayanathan, R. R. Eason, D. Zhang, F. A. Simmen, and R. C. M. Simmen Progesterone Receptor Transactivation of the Secretory Leukocyte Protease Inhibitor Gene in Ishikawa Endometrial Epithelial Cells Involves Recruitment of Kruppel-Like Factor 9/Basic Transcription Element Binding Protein-1
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F. A. Simmen and R. C. M. Simmen Orchestrating the Menstrual Cycle: Discerning the Music from the Noise.
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O. Y. Khan, G. Fu, A. Ismail, S. Srinivasan, X. Cao, Y. Tu, S. Lu, and Z. Nawaz Multifunction Steroid Receptor Coactivator, E6-Associated Protein, Is Involved in Development of the Prostate Gland
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T. Tsukahara, R. Tsukahara, S. Yasuda, N. Makarova, W. J. Valentine, P. Allison, H. Yuan, D. L. Baker, Z. Li, R. Bittman, et al. Different Residues Mediate Recognition of 1-O-Oleyllysophosphatidic Acid and Rosiglitazone in the Ligand Binding Domain of Peroxisome Proliferator-activated Receptor {gamma}
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M. D Heitzer and D. B. DeFranco Mechanism of Action of Hic-5/Androgen Receptor Activator 55, a LIM Domain-Containing Nuclear Receptor Coactivator
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W. M. Bryant, M. A. Gibson, and M. A. Shupnik Stimulation of the Novel Estrogen Receptor-{alpha} Intronic TERP-1 Promoter by Estrogens, Androgen, Pituitary Adenylate Cyclase-Activating Peptide, and Forskolin, and Autoregulation by TERP-1 Protein
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R. B. Lanz, Z. Jericevic, W. J. Zuercher, C. Watkins, D. L. Steffen, R. Margolis, and N. J. McKenna Nuclear Receptor Signaling Atlas (www.nursa.org): hyperlinking the nuclear receptor signaling community
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T. Ichijo, A. Voutetakis, A. P. Cotrim, N. Bhattachryya, M. Fujii, G. P. Chrousos, and T. Kino The Smad6-Histone Deacetylase 3 Complex Silences the Transcriptional Activity of the Glucocorticoid Receptor: POTENTIAL CLINICAL IMPLICATIONS
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