Modulation of Gonadotropin Levels by Peptides Acting at the Anterior Pituitary Gland
John J. Evans
University Department of Obstetrics and Gynaecology, Christchurch
School of Medicine, Christchurch, New Zealand
I. Introduction
II. Between the Hypothalamus and the Pituitary
III. Direct Modulatory Action by Peptides
IV. PituitaryReceptors
V. Interaction of Peptides with GnRH
VI. Self-Primingby GnRH and Desensitization
A. The effect of peptides on theGnRH-primed LH response
B. The effect of peptides on the desensitizedLH response toGnRH
VII. Steroids and the Ovulatory Cycleand the Effects on Peptide
Characteristics
VIII. IntrapituitaryPeptides
IX. Activity of Peptides in Vivo
X. InteractionAmong non-GnRH Peptides
XI. Processes Other Than SecretionThat Are Modulated by Peptides
XII. Summary and Conclusion
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