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Endocrine Reviews 19 (2): 144-172
Copyright © 1998 by The Endocrine Society

The Endocrine Effects of Nonhormonal Antineoplastic Therapy

Sai-Ching Jim Yeung, Alice Cua Chiu, Rena Vassilopoulou-Sellin and Robert F. Gagel

Joint Baylor College of Medicine-The University of Texas M. D. Anderson Cancer Center Endocrinology Fellowship Program (S.-C.J.Y., A.C.C.); and Section of Endocrinology (R.V.-S., R.F.G.), Department of Medical Specialties, The University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030

I. Introduction
II. Disorders of Glucose Metabolism
A. Diabetes mellitus
B. Glycosuria and ketonuria
III. Disorders of Free Water Clearance
A. Syndrome of inappropriate ADH (SIADH)
B. Nephrogenic diabetes insipidus
IV. Disorders of Mineral Metabolism
A. Hypocalcemia
B. Hypercalcemia
C. Hypomagnesemia
V. Metabolic Bone Diseases
A. Osteoporosis
B. Rickets or osteomalacia
VI. Thyroid Disorders
A. Serum thyroid hormone-binding protein abnormalities
B. Hypothyroidism
C. Thyrotoxicosis
D. Thyroid neoplasm
VII. Disorders of Lipid Metabolism
A. Hypertriglyceridemia
B. Hypercholesterolemia
VIII. Adrenal Dysfunction
A. Primary adrenal insufficiency
B. Secondary adrenal insufficiency
IX. Disorders of GH Secretion and Growth
A. GH deficiency
B. Growth retardation
X. Reproductive Dysfunction
A. Reproductive dysfunction due to hypothalamic-pituitary damage
B. Gonadal toxicity
XI. Prevention and Surveillance of Endocrine Side Effects
A. Pediatric screening
B. Adult screening.




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Copyright © 1998 by The Endocrine Society